Mass Spec for Post-Translational Modification (PTM) Analysis

Mass Spec for Post-Translational Modification (PTM) Analysis

Perform a range of applications from protein identification, to biomarker discovery, de novo sequencing and metabolite profiling, with confidence. The Thermo Scientific LTQ Orbitrap XL Ion Trap-Orbitrap Mass Spectrometer is based on Thermo Scientific LTQ XL linear ion trap and Orbitrap mass spectrometer technologies. To enhance the flexibility of fragmentation experiments for advanced proteomics and small molecule research, the instrument features an HCD collision cell.

Specifications:

• Resolution (apodized)
  • 60000 (FWHM) @ m/z 400 with a scan repetition rate of 1 second
  • Minimum resolution 7500@ m/z 400
  • Maximum resolution 100000 @ m/z 400
• Cycle Time 
  • 1 scan at 60000 resolution @ m/z 400 per second
• Mass Range 
  • m/z 50–2000
  • m/z 200–4000
• Mass Accuracy 
  • <3 ppm RMS for 2 h period with external calibration using defined conditions
  • <2 ppm RMS with internal calibration
• Dynamic Range 
  • >10000 between mass spectra,
  • >4000 between highest and lowest detectable mass in one spectrum
• MS/MS 
  • MS/MS and MSn scan functions