AB Sciex 4500 LC/MS/MS & Shimadzu 20a HPLC


  • AB Sciex 4500 LC/MS/MS
    • Turbo V Source
    • TurboIon Spray Probe
  • Shimadzu 20a HPLC
    • Degasser
    • Two (2) Pumps
    • Autosampler
    • Column Oven
  • Mechanical Pump
  • Analyst Data System
  • Warranty Coverage


  • MS Sample Introduction – Browse
  • Generator
  • Air Compressor
  • Workbench – Browse
  • Installation & Familiarization
  • Extended Warranty

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Item#: 11786
Condition: Tested
Manufacturer: AB Sciex

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AB Sciex 4500 LC/MS/MS & Shimadzu 20a HPLC

The AB Sciex 4500 LC/MS/MS is the intelligently re-engineered design of the 4000 QTRAP Platform, and sets a new benchmark for robust quantitation and library searching. The system is ideal for laboratories requiring ultimate robustness, ruggedness, and reliability for high-throughput screening of many compounds in many samples every day.

The AB SCIEX 4500  has been re-engineered to set a new benchmark for reliable quantitation and library searching - with 100 fold more full-scan sensitivity over basic triple quadrupoles in the same class. The LC/MS/MS covers key performance criteria: Quantitative sensitivity, dynamic range, scan speed, ionization source flow range, and footprint.


  • TurboV ionization source- The gold standard for LC-MS/MS ionization, the TurboV ionization source was made for demanding applications, with a patented design that delivers highly efficient desolvation for stable, sensitive performance across a wide range of flow rates from 50 uL/min up to 3 mL/min, with the versatility of ESI and APCI ionization capabilities and compatibility with microflow hybrid electrodes (to extend flow regime down to 5 uL/min) in the same source so you can run a wider scope of methods on your system.
  • Curtain gas interface- The curtain gas interface provides a wall of clean nitrogen to help prevent neutral components from entering the mass spec, so the system is more robust, requires less maintenance, and delivers increased uptime for your lab.  When tested against 1500 plasma injections, the combination of interface and source delivered consistent quantitative results with response CVs < 4%.
  • QJet ion guide- The QJet design is what brings the system reliability and sensitivity, providing increased uptime, reduced maintenance, and improved ion transmission efficiency which enhances overall sensitivity.
  • LINAC collision cell- The engineering of patented Qurved LINAC collision cell provides fast and efficient ion fragmentation, with insignificant crosstalk, so you are able to get higher quality MRM and MS/MS data, particularly for high-throughput methods with hundreds of compounds.
  • AcQuRate pulse counting detector- The AcQuRate pulse counting detector was designed for reproducibility and accuracy, providing excellent results for low level compound detection and a wide dynamic range.
  • Dynamic range- Achieve up to 5 orders of dynamic range for high performance quantitation in your first injection, reducing the needs for repeat analyses for increased productivity.
  • Mass range- The 5 to 2000 Da mass range allows flexibility to tackle a large scope of quantitation assays on your single mass spec system.
  • Ultra-fast MRM cycle times- With 1 minimum dwell times of 1 msec for MRM acquisition, you can screen for more compounds in every pass, increasing your throughput and data quality.

Shimadzu SIL-20AC Autosampler

  • Injection Method:  Metering pump, variable volume, no sample loss
  • Injection volume: 0.1 to 100 µL (std), 1 to 2,000 µL (opt)
  • Samples Capacity: 70 1.5 mL vials (incl. std.);
  • Control Rack: 10 1.5 mL vials
  • Injection Volume Accuracy: ± 1% (50µL, n=10)
  • Injection Volume Precision: RSD < 0.3% (10µL)

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AB Sciex 4500 LC/MS/MS & Shimadzu 20a HPLC

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