Thermo LXQ Linear Ion Trap MS/MS
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Designed for drug discovery, forensics, proteomics and a variety of industrial applications, the LXQ offers fast cycle time with the increased sensitivity of a linear ion trap.
The predecessor to the Thermo LTQ XL, the Thermo LXQ is an advanced linear ion trap mass spectrometer that comprises a syringe pump, a divert/inject valve, an MS detector, and the Xcalibur data system. The LXQ MS detector consists of an atmospheric pressure ionization (API) source, ion optics, mass analyzer, and ion detection system.
You can operate the LXQ using any of four ionization techniques: Electrospray Ionization (ESI); Atmospheric Pressure Chemical Ionization (APCI); Atmospheric Pressure Photoionization (APPI); Nanospray Ionization (NSI). Because these four techniques use the same ion source interface (that is, the portion of the API source that is under vacuum), you can switch between these in just a few minutes. Switching ionization techniques merely involves switching the probes and does not break vacuum.
- High sensitivity for detection of multiple analytes in complex matrices
- Confident structural identification and quantification
- Fast cycle times for high-throughput analyses
- Patented linear ion trap design enables high-quality MSn characterization
- Routine protein and peptide analysis
The LXQ's combination of fast cycle time and high spectral quality is key to quickly screening for drugs and their metabolites. The LXQ’s high accuracy and precision for quantitative analysis, along with a linear dynamic range of four orders of magnitude, delivers quantification and robustness for forensics. Increase your productivity with the outstanding robustness of the LXQ and the Ion Max source. The LXQ delivers highly sensitive, rapid screening for proteomics.
Application Notes & More Information (links) :
Brochure | Thermo Finnigan LXQ
Article | Performance Evaluation of Three Liquid Chromatography Mass Spectrometry Methods for Broad Spectrum Drug Screening
AN 369 | A High Throughput Approach for Metabolite Proﬁling and Characterization Using the LXQ Linear Ion Trap Mass Spectrometer
AN 449 | A Complete Forensic Toxicology Screening Procedure for Drugs and Toxic Compounds in Urine and Plasma Using LC-MS/MS
AN 517 | Screening for Drugs and Toxic Compounds: Comparison between lc-ms/ms, hplc-dad, and Immunoassay