Thermo Electron Transfer Dissociation (ETD) for LTQ Series Mass Specs
Achieve better analysis of proteins and their post-translational modifications (PTMs) with the Thermo Scientific Electron Transfer Dissociation (ETD) option. Unlike CID, which cleaves weakly bound modifications off the peptide backbone, ETD induces fragmentation along the peptide backbone in a sequence-independent manner, leaving labile modifications linked to the peptide chain. This greatly simplifies identification of modification sites. ETD produces primarily c- and z-type fragment ions that complement the b- and y-type ions produced by CID, increasing sequence coverage and protein IDs.
Electron transfer dissociation is a supremely useful tool for the analysis of post-translationally modified proteins. ETD capability can be added to many Thermo Scientific ion trap mass spectrometers.
- ETD preserves labile PTMs, allowing straightforward identification of the peptide sequence and the site of modification>
- For top-down analysis, ETD can be combined with proton transfer reaction (PTR) which dramatically simplifies spectra from intact proteins
- For workflows that include low-mass isobaric mass tags, ETD can be combined with pulsed-Q dissociation (PQD) which eliminates the normal low-mass cutoff
- ETD can be added to most Thermo Scientific LTQ-series ion trap and hybrid ion trap-Orbitrap mass spectrometers
- Proteome Discoverer software includes the proprietary Z-Core database search algorithm specifically optimized for ETD spectra
- Proteome Discoverer software can easily merge complementary CID and ETD results to maximize protein sequence coverage
Expertly refurbished used laboratory instruments
Every instrument we sell undergoes a complete inspection of all electronics and performance review. The instruments undergo in-depth preventative maintenance procedures that include extensive cleaning, detector maintenance, line and pump flushing. Routine maintenance is also addressed and filters, liners, tubing, etc. are all replaced as needed. Our chemist perform full calibration and data verification. The once used Mass Spec Accessories are returned to like-new condition and will run your samples for 30-80% less than OEM pricing.
This refurbished Thermo Electron Transfer Dissociation (ETD) for LTQ Series Mass Specs is calibrated to meet OEM standards. Our expert service engineers and chemists can install and custom configure the system to be compliant with the Methods you plan to run.
The GenTech Difference
Why Buy New When You Don't Have To? Our refurbished Mass Spec Accessories have been expertly restored to meet OEM standards. GenTech is a full service reseller, our knowledgeable engineers perform installations, repairs, training and application setup. The inventory in our 60,000 sq. foot facility is constantly changing with new shipments coming in daily. GenTech customers receive lifetime phone support for all instruments they purchase.
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GenTech buys a wide range of equipment from Agilent, Thermo, Waters, AB Sciex, Shimadzu, Perkin Elmer, and More! Since 1996 GenTech Scientific has purchased used laboratory equipment to refurbish and resell with 1 Year warranties. Our refurbished equipment comes fully tested, and supported long after the manufacturers! If you have old or unused lab equipment in your laboratory that you are looking to sell, contact GenTech and see how we can help you!
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