Shimadzu 8050 Right Angle
Shimadzu 8050 Left Angle

Shimadzu 8050 Triple Quad LC/MS




Includes:

  • Shimadzu 8050 Triple Quad LC/MS
  • Mechanical Pump
  • Data System
  • Warranty Coverage

Options:

  • MS Sample Introduction
  • Generator
  • Air Compressor
  • Workbench
  • Wiley Registry / NIST 2023 Mass Spectral Library
  • Installation & Familiarization
  • Extended Warranty
  • Financing Available


15-Day

Refurbishment cadence

OEM-Spec

Verified against OEM and published benchmarks; report included.

On-Staff

Solution Scientists

Since 1996

Three decades supporting labs

The System

What you are buying

A refurbished Shimadzu LCMS-8050 LC-MS/MS system. The liquid chromatograph separates the mixture and delivers it to the ion source. The source converts the eluent into gas-phase ions. The triple quadrupole isolates a precursor, fragments it, and measures the product ion for trace-level quantitation. GenTech rebuilds and tests the LC, the source, and the analyzer, then verifies the system end to end.

Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.

What Agilent says about this platform

Shimadzu built the LCMS-8050 around UF scanning technology, reaching scan speeds up to 30,000 u per second. The instrument controls quadrupole voltage dynamically based on scan speed and m/z, which holds data collection at 0.1 u intervals even at maximum speed, preserving sensitivity and mass accuracy that would otherwise degrade at high scan rates. Positive and negative ion polarity switches in 5 milliseconds, fast enough to collect sufficient data points across the narrow peaks UHPLC produces. The system can run MS/MS scans and MRM measurements concurrently without losing quantitative accuracy. A documented case study quantified verapamil in blood plasma from 500 attograms to 50 picograms on the LCMS-8050, holding %RSD to 2.77 percent at the 500-attogram level.

 

What each module does

Liquid chromatograph

Separates the mixture and delivers a reproducible gradient to the source. This listing does not specify a bundled HPLC brand; a compatible front end is sold separately or paired at the bench.

Ion source

Converts the liquid eluent into gas-phase ions ahead of the analyzer, handling the polarity switching needed for simultaneous positive and negative ion methods.

Mass analyzer

Two quadrupoles flank a collision cell. The first selects a precursor, the cell fragments it, and the second measures a product ion, running MS/MS scans and MRM measurements in the same acquisition.

Vacuum and detection

Stages the ions from atmosphere to high vacuum, then counts them at the detector.

In this stack
Triple Quadrupole MS LCMS-8050 Verified
1260 Vialsampler G7129A Verified
1260 Multicolumn Thermostat G7116A Verified
1260 Diode Array Detector G7115A Verified
Workstation loaded with software
Included
Specifications

Technical detail

Analyzer Triple quadrupole
Scan speed Up to 30,000 u/sec
Mass range m/z 2 to 2,000
Software Loaded on computer
HPLC front end Sold separately
Polarity switching 5 msec
Data collection resolution 0.1 u intervals, maintained at max speed

*OEM specifications for brand new instrument.

Certification

What “GenTech Certified” means

Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.

1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.

2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.

3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.

4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.

5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.

Application Fit

Labs that run this system

The Shimadzu 8050 LC/MS is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.

Environmental

PFAS testing

EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.

Food & Beverage / Cannabis

Pesticides and mycotoxins

Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.

Pharmaceutical

Trace impurities and cleaning validation

Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.

Clinical & Forensic

Quantitative toxicology

Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.

Regulated Bioanalysis

GLP-grade quantitation

Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.

Model

8050

OEM

Shimadzu

Financing

Financing Options Available

Financing Options Available.  Finance Builder.

Need a main board instead?

Replacing a failed pump or looking to upgrade your mass spec? Every module in this system is available individually, in stock and performance-verified.