Agilent 1260 Degasser Right Angle
Agilent 1260 Degasser Front View without Cover

Agilent 1260 Infinity HPLC Degasser




Includes:

  • Agilent 1260 Infinity HPLC Degasser
  • In-House Warranty Coverage

Options:



15-Day

Refurbishment cadence

OEM-Spec

Verified against OEM and published benchmarks; report included.

On-Staff

Solution Scientists

Since 1996

Three decades supporting labs

The System

What you are buying

A refurbished Agilent 1260 Infinity G4225A vacuum degasser. It removes dissolved gas from the mobile phase, which steadies the baseline and protects the pump.

Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.

What Agilent says about this platform

Agilent built the G4225A around four separate vacuum chambers, each with its own semipermeable tubing, paired with a vacuum pump and control assembly. Switching the degasser on triggers the control assembly to run the vacuum pump, which pulls the chambers down to low pressure. A pressure sensor measures that vacuum. The degasser holds it steady through a controlled leak in the air inlet filter combined with pump regulation. The LC pump draws solvent from the bottles through the semipermeable tubing in each vacuum chamber. Dissolved gas in the solvent permeates through the tubing walls into the vacuum chambers as it passes through. The solvent leaves the outlet already degassed. Each channel handles flow up to 10 milliliters per minute.

 

What each module does

Vacuum degassing

Keeps bubbles out of the flow path, which matters most at low flow and high sensitivity.

In this stack
Agilent 1260 Infinity Degasser G4225A Verified
Agilent 1260 Infinity Degasser G4225A Verified
1260 Multicolumn Thermostat G7116A Verified
1260 Diode Array Detector G7115A Verified
Workstation loaded with software
Included
Specifications

Technical detail

Channels 4, independent vacuum chambers
Max flow rate 10 mL/min per channel
Vacuum regulation Pressure sensor, controlled air-inlet leak
Membrane design Semipermeable tubing per chamber
Control Onboard control assembly
Software Loaded on workstation

*OEM specifications for brand new instrument.

Certification

What “GenTech Certified” means

Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.

1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.

2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.

3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.

4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.

5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.

Application Fit

Labs that run this system

The 1260 HPLC is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.

Pharmaceutical QC

Assay, Impurity and dissolution

The 1260 transfers cleanly into USP monograph assays, related-substance profiling, and dissolution testing. Quaternary blending simplifies mobile-phase transfer between labs.

Environmental

EPA HPLC methods

Diode array detection supports EPA HPLC methods for contaminants and residues in water and soil, including PAHs, explosives, and carbamates.

Food & Beverage

Additives and vitamins

The system quantifies preservatives, sweeteners, organic acids, and fat-soluble vitamins at the throughput a production-support lab needs.

Cannabis & Hemp

Cannabinoid potency

HPLC with UV detection is the reference technique for potency. The 1260 resolves the major cannabinoids for compliance and label-claim testing.

Natural Products

Botanical actives

Labs quantify polyphenols, flavonoids, and marker compounds in extracts and nutraceutical formulations across long, reproducible sequences.

Clinical & Forensic

Screening and drug monitoring

The 1260 runs HPLC-UV workflows for therapeutic drug monitoring and drugs-of-abuse screening, where method portability and uptime matter more than peak novelty.

Chemical & Materials

Purity and additives

Industrial labs separate and quantify synthesis intermediates, polymer additives, and stabilizers for QC and release testing.

Method Development

Four-solvent scouting

Agilent recommends the quaternary pump for method development. Blend up to four solvents to scout selectivity before you lock a final method.

LC/MS Front End

Proteomics, metabolomics, lipidomics

Many omics workflows use mass spectrometry for detection and rely on LC for separation. The 1200 serves as the front end feeding your MS or fraction collector.

Condition

Refurbished

Model

G4425A

OEM

Agilent Technologies

Financing

Financing Options Available

Financing Options Available.  Finance Builder.

Need a single module instead?

Replacing a failed pump or expanind an existing stack? Every module in this system is available individually, in stock and performance-verified.