15-Day
Refurbishment cadence
OEM-Spec
Verified against OEM and published benchmarks; report included.
On-Staff
Solution Scientists
Since 1996
Three decades supporting labs
What you are buying
A refurbished Agilent 6530 Q-TOF LC/MS with a 1260 HPLC front end. The 1260 pump and sampler separate the mixture and deliver a reproducible gradient to the source. The 6530’s ion source converts the eluent into gas-phase ions. The quadrupole and time-of-flight analyzer record accurate-mass spectra for screening, characterization, and unknown identification. GenTech rebuilds and tests the LC, the source, and the analyzer, then verifies the system end to end.
Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.
What Agilent says about this platform
Agilent built the 6530 around a quadrupole and time-of-flight analyzer covering a mass range of m/z 100 to 20,000 in extended mass mode. Mass resolving power exceeds 20,000 FWHM at m/z 1,522, with mass accuracy within 2 to 3 parts per million across repeat injections. Agilent rates MS-mode sensitivity at 1 picogram of reserpine on-column at a 400-microliter-per-minute flow rate, with a signal-to-noise ratio of 200 to 1 while holding that same resolution. MS/MS mode reaches a signal-to-noise ratio of 500 to 1 on the most intense product ions. The 6530 can pair with the Agilent Jet Stream ion source, which uses a super-heated nitrogen sheath gas to confine the electrospray and reported roughly a five-fold gain in signal intensity over a conventional ESI source. MassHunter software handles profiling, characterization, identification, and quantification. The system pairs with UHPLC, 2D-LC, SFC, or GC-APCI chromatographic interfaces.
What each module does
Liquid chromatograph
Separates the mixture and delivers a reproducible gradient to the source. The 1260 front end runs the same pumps, samplers, and detectors as a standalone HPLC.
Ion source
Converts the liquid eluent into gas-phase ions. Electrospray and Agilent Jet Stream handle polar and large molecules; atmospheric-pressure chemical ionization covers the less-polar compounds.
Mass analyzer
A quadrupole selects ions; a time-of-flight analyzer measures their mass to high accuracy and resolution, which supports accurate-mass screening and the characterization of proteins, metabolites, and unknowns.
Vacuum and detection
Stages the ions from atmosphere to high vacuum, then counts them at the detector.
| In this stack | |
| Q-TOF MS G6530 A/B | Verified |
| 1260 Vialsampler G7129A | Verified |
| 1260 Multicolumn Thermostat G7116A | Verified |
| 1260 Diode Array Detector G7115A | Verified |
|
Workstation loaded with software
|
Included |
| Each module is individually serialized and performance-verified before the stack is assembled and tested as a complete system. | |
Technical detail
| Analyzer | Quadrupole + time-of-flight |
| Mass range | m/z 100 to 20,000 (extended mode) |
| Resolution | >20,000 FWHM at m/z 1,522 |
| Software | MassHunter |
| 1290 Infinity Front End | Agilent HPLC |
| Max pressure | 400 bar |
| Pump options | Isocratic, binary, quaternary |
*OEM specifications for brand new instrument.
What “GenTech Certified” means
Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.
1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.
2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.
3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.
4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.
5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.
Labs that run this system
The 6530 is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.
PFAS testing
EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.
Pesticides and mycotoxins
Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.
Trace impurities and cleaning validation
Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.
Quantitative toxicology
Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.
GLP-grade quantitation
Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.
| Model | 6530, 1260 |
|---|---|
| OEM | Agilent Technologies |
| Financing | Financing Options Available |
Financing Options Available. Finance Builder.
Need a main board instead?
Replacing a failed pump or looking to upgrade your mass spec? Every module in this system is available individually, in stock and performance-verified.







