6530 with 1260 front end

Agilent 6530 Q-TOF LC/MS with 1260 HPLC Front End




Includes:

  • Agilent 6530 Q-TOF LC/MS
  • Agilent 1260 HPLC Front End
    • Solvent Tray
    • Degasser
    • Binary Pump
    • Autosampler
  • Data System
  • Warranty Coverage

Options:

  • Module Customization Available Browse
  • MS Sample Introduction
  • Installation Kits – Browse
  • Generator
  • Air Compressor
  • Workbench – Browse
  • Installation & Familiarization
  • Extended Warranty
  • Financing Available


15-Day

Refurbishment cadence

OEM-Spec

Verified against OEM and published benchmarks; report included.

On-Staff

Solution Scientists

Since 1996

Three decades supporting labs

The System

What you are buying

A refurbished Agilent 6530 Q-TOF LC/MS with a 1260 HPLC front end. The 1260 pump and sampler separate the mixture and deliver a reproducible gradient to the source. The 6530’s ion source converts the eluent into gas-phase ions. The quadrupole and time-of-flight analyzer record accurate-mass spectra for screening, characterization, and unknown identification. GenTech rebuilds and tests the LC, the source, and the analyzer, then verifies the system end to end.

Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.

What Agilent says about this platform

Agilent built the 6530 around a quadrupole and time-of-flight analyzer covering a mass range of m/z 100 to 20,000 in extended mass mode. Mass resolving power exceeds 20,000 FWHM at m/z 1,522, with mass accuracy within 2 to 3 parts per million across repeat injections. Agilent rates MS-mode sensitivity at 1 picogram of reserpine on-column at a 400-microliter-per-minute flow rate, with a signal-to-noise ratio of 200 to 1 while holding that same resolution. MS/MS mode reaches a signal-to-noise ratio of 500 to 1 on the most intense product ions. The 6530 can pair with the Agilent Jet Stream ion source, which uses a super-heated nitrogen sheath gas to confine the electrospray and reported roughly a five-fold gain in signal intensity over a conventional ESI source. MassHunter software handles profiling, characterization, identification, and quantification. The system pairs with UHPLC, 2D-LC, SFC, or GC-APCI chromatographic interfaces.

 

What each module does

Liquid chromatograph

Separates the mixture and delivers a reproducible gradient to the source. The 1260 front end runs the same pumps, samplers, and detectors as a standalone HPLC.

Ion source

Converts the liquid eluent into gas-phase ions. Electrospray and Agilent Jet Stream handle polar and large molecules; atmospheric-pressure chemical ionization covers the less-polar compounds.

Mass analyzer

A quadrupole selects ions; a time-of-flight analyzer measures their mass to high accuracy and resolution, which supports accurate-mass screening and the characterization of proteins, metabolites, and unknowns.

Vacuum and detection

Stages the ions from atmosphere to high vacuum, then counts them at the detector.

In this stack
Q-TOF MS G6530 A/B Verified
1260 Vialsampler G7129A Verified
1260 Multicolumn Thermostat G7116A Verified
1260 Diode Array Detector G7115A Verified
Workstation loaded with software
Included
Specifications

Technical detail

Analyzer Quadrupole + time-of-flight
Mass range m/z 100 to 20,000 (extended mode)
Resolution >20,000 FWHM at m/z 1,522
Software MassHunter
1290 Infinity Front End Agilent HPLC
Max pressure 400 bar
Pump options Isocratic, binary, quaternary

*OEM specifications for brand new instrument.

Certification

What “GenTech Certified” means

Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.

1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.

2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.

3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.

4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.

5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.

Application Fit

Labs that run this system

The 6530 is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.

Environmental

PFAS testing

EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.

Food & Beverage / Cannabis

Pesticides and mycotoxins

Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.

Pharmaceutical

Trace impurities and cleaning validation

Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.

Clinical & Forensic

Quantitative toxicology

Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.

Regulated Bioanalysis

GLP-grade quantitation

Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.

Model

6530, 1260

OEM

Agilent Technologies

Financing

Financing Options Available

Financing Options Available.  Finance Builder.

Need a main board instead?

Replacing a failed pump or looking to upgrade your mass spec? Every module in this system is available individually, in stock and performance-verified.