15-Day
Refurbishment cadence
OEM-Spec
Verified against OEM and published benchmarks; report included.
On-Staff
Solution Scientists
Since 1996
Three decades supporting labs
What you are buying
Pharmaceutical, environmental, and clinical methods that quantify trace compounds by mass run on the LC-MS the Agilent 6430 delivers. The liquid chromatograph separates the mixture; the ion source converts the eluent into gas-phase ions; the triple quadrupole isolates a precursor, fragments it, and measures the product ions down to parts per trillion. GenTech rebuilds and tests the LC, the source, and the analyzer, then verifies the system end to end. You receive an LC-MS that arrives tuned and ready to run your methods.
Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.
What Agilent says about this platform
Agilent built the 6430 as a step up from the entry-level 6410, adding a second turbo pump, improved pumping in the second vacuum stage, and updated collision cell lenses. MS cycle times run as short as 100 milliseconds, capturing at least ten data points across a one-second peak. Dwell time runs as low as 1 millisecond. A resistively coated capillary lets the instrument switch polarity and resume data acquisition within 30 milliseconds. The system supports up to 19,800 MRM transitions, with up to 4,000 dynamic MRM transitions per method. Agilent rates sensitivity at 1 picogram of reserpine on-column, with a signal-to-noise ratio around 300 to 1. Mass resolution runs to 0.5 Da full width at half maximum with manual tuning, or 0.7 Da with autotune. MassHunter software controls acquisition and data analysis. Agilent Jet Stream technology is not part of the 6430; that ion source is reserved for the 6460 and higher models in the triple quadrupole line.
What each module does
Liquid chromatograph
Separates the mixture and delivers a reproducible gradient to the source. This listing does not specify a bundled HPLC brand; a compatible front end is sold separately or paired at the bench.
Ion source
Converts the liquid eluent into gas-phase ions, compatible with Agilent’s HPLC-Chip interface for chip-based separations.
Mass analyzer
Two quadrupoles flank a collision cell, with a second turbo pump and updated collision cell lenses over the entry-level 6410. The first selects a precursor, the cell fragments it, and the second measures a product ion, which gives the selectivity and sensitivity that trace quantitation in complex matrices demands.
Vacuum and detection
Stages the ions from atmosphere to high vacuum, then counts them at the detector.
| In this stack | |
| Triple Quadrupole MS G6430A | Verified |
| 1260 Vialsampler G7129A | Verified |
| 1260 Multicolumn Thermostat G7116A | Verified |
| 1260 Diode Array Detector G7115A | Verified |
|
Workstation loaded with software
|
Included |
| Each module is individually serialized and performance-verified before the stack is assembled and tested as a complete system. | |
Technical detail
| MS cycle time | As short as 100 ms |
| Dwell time | As low as 1 ms |
| Polarity switching | 30 ms |
| MRM capacity | Up to 19,800 transitions (4,000 dynamic) |
| HPLC front end | Sold separately; pairs with 1100 or 1200 Series |
| Sensitivity | 1 pg reserpine, ~300:1 S/N |
| Mass resolution | 0.5 Da (manual), 0.7 Da (autotune) |
*OEM specifications for brand new instrument.
What “GenTech Certified” means
Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.
1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.
2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.
3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.
4. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.
Labs that run this system
The 6430 is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.
PFAS testing
EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.
Pesticides and mycotoxins
Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.
Trace impurities and cleaning validation
Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.
Quantitative toxicology
Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.
GLP-grade quantitation
Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.
| Weight | 400 lbs |
|---|---|
| Dimensions | 48 × 48 × 40 in |
| Condition | Refurbished |
| Model | 6430 |
| OEM | Agilent |
| Financing | Financing Options Available |
Financing Options Available. Finance Builder.
Need a main board instead?
Replacing a failed pump or looking to upgrade your mass spec? Every module in this system is available individually, in stock and performance-verified.
