15-Day
Refurbishment cadence
OEM-Spec
Verified against OEM and published benchmarks; report included.
On-Staff
Solution Scientists
Since 1996
Three decades supporting labs
What you are buying
A professionally refurbished AB Sciex API 4000 triple quadrupole mass spectrometer. Pair with a compatible front end to build a high performance LC-MS/MS system: The liquid chromatograph front end separates the mixture and delivers it to the ion source. The source converts the eluent into gas-phase ions. The triple quadrupole isolates a precursor, fragments it, and measures the product ion for trace-level quantitation. GenTech rebuilds and tests the MS, the source, and the analyzer, then verifies the system end to end.
Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.
What the OEM says about this platform
AB Sciex designed the API 4000 Triple Quadrupole Mass Spectrometer to establish the benchmark for sensitivity, selectivity, and ruggedness in high-throughput laboratories. The OEM emphasizes the platform’s patented LINAC® (Linear Acceleration) collision cell technology, which eliminates cross-talk and ensures rapid multi-reaction monitoring (MRM) transitions without sacrificing signal intensity. Positioned by Sciex as the premier workhorse for ADME/Tox, clinical trials, environmental testing, and forensic screening, the API 4000 is engineered to easily handle highly complex biological and environmental matrices while maintaining superior quantitative reproducibility over long analytical runs.
What each component does
- API 4000 Triple Quadrupole Mass Spectrometer: Isolates, fragments, and detects targeted compounds based on their mass-to-charge ratio, utilizing tandem quadrupole technology for precise molecular quantification.
- Turbo V™ Ion Source: Efficiently ionizes liquid samples using an optimized orthogonal spray design, significantly reducing contamination and enhancing sensitivity across broad flow rates.
- Mechanical Roughing Vacuum Pump: Provide the critical backing pressure required to sustain the high-vacuum conditions inside the analyzer chamber.
- Data System: Serves as the central command software to configure instrument methods, control LC-MS/MS data acquisition, and process quantitative batch samples.
- Liquid chromatograph: Separates the mixture and delivers a reproducible gradient to the source. This listing does not include, or specify a bundled HPLC brand; a compatible front end is sold separately or paired at the bench.
| In this stack | |
| AB Sciex API 4000 API 4000 | Verified |
| Mechanical Pump | Verified |
| Warranty Coverage Extended Options Available | Included |
| Workstation with preloaded software | Included |
| Each module is individually serialized and performance-verified before the stack is assembled and tested as a complete system. | |
Technical detail
| Analyzer | Triple quadrupole |
| Mass range | m/z 5 to 2,800 |
| Collision cell | LINAC, pressurized ceramic housing |
| Ion source | Turbo V, TurboIonSpray/APCI probes |
| Software | Analyst |
*OEM specifications for brand new instrument.
What “GenTech Certified” means
Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.
1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.
2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.
3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.
4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.
5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.
Labs that run this system
The AB Sciex QTrap 5500 is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.
PFAS testing
EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.
Pesticides and mycotoxins
Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.
Trace impurities and cleaning validation
Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.
Quantitative toxicology
Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.
GLP-grade quantitation
Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.
| Weight | 350 lbs |
|---|---|
| Dimensions | 60 × 60 × 60 in |
| Model | API 4000 |
| OEM | AB Sciex |
| Financing | Financing Options Available |
Financing Options Available. Finance Builder.
Need a front end?
Everything you need to build your LC/MS system is available individually or as a system, in stock and performance-verified.
